Gene
alg6
- ID
- ZDB-GENE-040808-45
- Name
- ALG6 alpha-1,3-glucosyltransferase
- Symbol
- alg6 Nomenclature History
- Previous Names
-
- zgc:100813 (1)
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in oligosaccharide-lipid intermediate biosynthetic process and protein N-linked glycosylation. Predicted to act upstream of or within dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ic. Orthologous to human ALG6 (ALG6 alpha-1,3-glucosyltransferase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6901735 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital disorder of glycosylation Ic | Alliance | Congenital disorder of glycosylation, type Ic | 603147 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR004856 | Glycosyl transferase, ALG6/ALG8 |
Domain Details Per Protein
| Protein | Length | Glycosyl transferase, ALG6/ALG8 |
|---|---|---|
|
UniProtKB:A0A8M3B3H3
|
295 | |
|
UniProtKB:A0A8M1N1I1
|
506 | |
|
UniProtKB:Q6AXK8
|
227 |
Interactions and Pathways
No data available
Plasmids
No data available