Gene

auh

ID
ZDB-GENE-040801-95
Name
AU RNA binding protein/enoyl-CoA hydratase
Symbol
auh Nomenclature History
Previous Names
  • wu:fb81b10
  • zgc:101057
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to have enoyl-CoA hydratase activity. Predicted to be involved in fatty acid beta-oxidation. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria type 1 and renal tubular transport disease. Orthologous to human AUH (AU RNA binding methylglutaconyl-CoA hydratase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Pei et al., 2010
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With auh Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
3-methylglutaconic aciduria type 1 Alliance 3-methylglutaconic aciduria, type I 250950
Associated With auh Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018376 Enoyl-CoA hydratase/isomerase, conserved site
Family IPR001753 Enoyl-CoA hydratase/isomerase
Homologous_superfamily IPR014748 Enoyl-CoA hydratase, C-terminal
Homologous_superfamily IPR029045 ClpP/crotonase-like domain superfamily
Domain Details Per Protein
Protein Length ClpP/crotonase-like domain superfamily Enoyl-CoA hydratase, C-terminal Enoyl-CoA hydratase/isomerase Enoyl-CoA hydratase/isomerase, conserved site
UniProtKB:F1RDX1 325
UniProtKB:Q6DC25 325
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations