Gene

rasgef1bb

ID
ZDB-GENE-040801-220
Name
RasGEF domain family, member 1Bb
Symbol
rasgef1bb Nomenclature History
Previous Names
  • fc34e01
  • rasgef (1)
  • im:7136415
  • wu:fc34e01
  • zgc:91814
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in Ras protein signal transduction. Predicted to act upstream of or within small GTPase-mediated signal transduction. Predicted to be active in plasma membrane. Is expressed in nervous system; notochord; oocyte; pectoral fin; and pharyngeal arch. Orthologous to human RASGEF1B (RasGEF domain family member 1B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
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Sequence Targeting Reagents
No data available
Human Disease
Associated With rasgef1bb Human Ortholog
No data available
Associated With rasgef1bb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019804 Ras guanine-nucleotide exchange factor, conserved site
Domain IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
Domain IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
Family IPR008937 Ras-like guanine nucleotide exchange factor
Homologous_superfamily IPR023578 Ras guanine nucleotide exchange factor domain superfamily
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Domain Details Per Protein
Protein Additional Resources Length Ras guanine-nucleotide exchange factor, catalytic domain superfamily Ras guanine-nucleotide exchange factor, conserved site Ras guanine nucleotide exchange factor domain superfamily Ras guanine-nucleotide exchange factors catalytic domain Ras-like guanine nucleotide exchange factor Ras-like guanine nucleotide exchange factor, N-terminal
UniProtKB:Q6DBW1 InterPro 475
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 10
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA rasgef1bb-201 (1) Ensembl 2,173 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACDKEYP-41F9ZFIN Curated Data
EncodesESTfc34e01
EncodesESTIMAGE:7136415Thisse et al., 2004
EncodescDNAMGC:91814ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanRASGEF1B4
Amino acid sequence comparison (3)
Conserved genome location (synteny) (1)
MouseRasgef1b5
Amino acid sequence comparison (1)
Conserved genome location (synteny) (1)
Citations
1 - 7 of 7
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