Gene
limk2
- ID
- ZDB-GENE-040718-398
- Name
- LIM domain kinase 2
- Symbol
- limk2 Nomenclature History
- Previous Names
-
- wu:fa97c09
- wu:fk73e11
- zgc:91990
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in actin cytoskeleton organization. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including axial vasculature; cephalic musculature; digestive system; mid cerebral vein; and nervous system. Orthologous to human LIMK2 (LIM domain kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Ott et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR001781 | Zinc finger, LIM-type |
| Family | IPR050940 | Actin-regulating Serine/Threonine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | Actin-regulating Serine/Threonine Kinase | PDZ domain | PDZ superfamily | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DG29
|
651 |
Interactions and Pathways
No data available
Plasmids
No data available