Gene
limk2
- ID
- ZDB-GENE-040718-398
- Name
- LIM domain kinase 2
- Symbol
- limk2 Nomenclature History
- Previous Names
-
- wu:fa97c09
- wu:fk73e11
- zgc:91990
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Predicted to be involved in actin cytoskeleton organization. Predicted to localize to cytoplasm and nucleus. Is expressed in several structures, including axial vasculature; cephalic musculature; digestive system; mid cerebral vein; and nervous system. Orthologous to human LIMK2 (LIM domain kinase 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from Ott et al., 2007
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR001478 | PDZ domain |
| Domain | IPR001781 | Zinc finger, LIM-type |
| Family | IPR050940 | Actin-regulating Serine/Threonine Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036034 | PDZ superfamily |
Domain Details Per Protein
| Protein | Length | Actin-regulating Serine/Threonine Kinase | PDZ domain | PDZ superfamily | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain | Zinc finger, LIM-type |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6DG29
|
651 |
Interactions and Pathways
No data available
Plasmids
No data available