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Gene

sirt5

ID
ZDB-GENE-040718-349
Name
sirtuin 5
Symbol
sirt5 Nomenclature History
Previous Names
  • zgc:92288
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Enables acyl binding activity and heterocyclic compound binding activity. Predicted to be involved in protein deacylation and regulation of ketone biosynthetic process. Predicted to be located in cytoplasm and nucleus. Predicted to be active in cytosol and mitochondrion. Is expressed in liver and retina. Orthologous to human SIRT5 (sirtuin 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sirt5 Human Ortholog
No data available
Associated With sirt5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR026590 Sirtuin family, catalytic core domain
Family IPR003000 Sirtuin family
Family IPR027546 Sirtuin, class III
Homologous_superfamily IPR026591 Sirtuin, catalytic core small domain superfamily
Homologous_superfamily IPR029035 DHS-like NAD/FAD-binding domain superfamily
Domain Details Per Protein
Protein Length DHS-like NAD/FAD-binding domain superfamily Sirtuin, catalytic core small domain superfamily Sirtuin, class III Sirtuin family Sirtuin family, catalytic core domain
UniProtKB:Q6DHI5 305
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-sirt5 polyclonal IgG Rabbit
  • WB
Abcam plc
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations