Gene
rab11bb
- ID
- ZDB-GENE-040718-293
- Name
- RAB11B, member RAS oncogene family, b
- Symbol
- rab11bb Nomenclature History
- Previous Names
-
- zgc:92772
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Predicted to enable GTP binding activity and GTPase activity. Predicted to be involved in constitutive secretory pathway and regulated exocytosis. Predicted to be active in Golgi apparatus and recycling endosome. Is expressed in cardiovascular system; nervous system; pharyngeal arch; pronephric duct; and spinal cord neural tube. Orthologous to human RAB11B (RAB11B, member RAS oncogene family).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:92772 (8 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Sheng et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | 617807 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | P-loop containing nucleoside triphosphate hydrolase | Rab GTPases family involved in membrane trafficking | Small GTPase | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6DGU2
|
218 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| aberrant processed transcript |
rab11bb-202
(1)
|
Ensembl | 830 nt | ||
| mRNA |
rab11bb-201
(1)
|
Ensembl | 1,176 nt |
Interactions and Pathways
No data available
Plasmids