Gene
s100b
- ID
- ZDB-GENE-040718-290
- Name
- S100 calcium binding protein, beta (neural)
- Symbol
- s100b Nomenclature History
- Previous Names
-
- si:dkey-110p14.2
- wu:fq18b10
- zgc:92776
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable several functions, including RAGE receptor binding activity; S100 protein binding activity; and calcium-dependent protein binding activity. Predicted to be involved in positive regulation of canonical NF-kappaB signal transduction and positive regulation of cell population proliferation. Predicted to act upstream of or within cell adhesion. Predicted to be located in extracellular region. Predicted to be active in cytoplasm; extracellular space; and nucleus. Is expressed in several structures, including digestive system; heart; integument; nervous system; and renal system. Human ortholog(s) of this gene implicated in Alzheimer's disease; aspergillosis; and schizophrenia. Orthologous to human S100B (S100 calcium binding protein B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | EF-hand domain | EF-hand domain pair | Protein S100-B | S100/CaBP-9k-type, calcium binding, subdomain | S100/Calcium binding protein 7/8-like, conserved site |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q6DGT8 | InterPro | 95 |
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-s100 | polyclonal | Rabbit |
|
Dako North America, Inc.
|
80 |
Plasmids
No data available