Gene

rpl11

ID
ZDB-GENE-040625-147
Name
ribosomal protein L11
Symbol
rpl11 Nomenclature History
Previous Names
  • zgc:86748
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Acts upstream of or within several processes, including erythrocyte development; glucose homeostasis; and hemoglobin biosynthetic process. Predicted to be located in ribosome. Predicted to be part of cytosolic large ribosomal subunit. Is expressed in endodermal cell; eye; intestine; liver; and pancreas. Used to study Diamond-Blackfan anemia. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 7 and T-cell acute lymphoblastic leukemia. Orthologous to human RPL11 (ribosomal protein L11).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
37 figures from 16 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rpl11 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Diamond-Blackfan anemia 7 Alliance Diamond-Blackfan anemia 7 612562
Associated With rpl11 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR020929 Ribosomal protein L5, conserved site
Domain IPR031309 Ribosomal protein L5, C-terminal
Domain IPR031310 Ribosomal protein L5, N-terminal
Family IPR002132 Ribosomal protein L5
Homologous_superfamily IPR022803 Ribosomal protein L5 domain superfamily
Domain Details Per Protein
Protein Length Ribosomal protein L5 Ribosomal protein L5, conserved site Ribosomal protein L5, C-terminal Ribosomal protein L5 domain superfamily Ribosomal protein L5, N-terminal
UniProtKB:Q6IQI6 178
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-rpl11 polyclonal Rabbit
  • WB
Abcam plc
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations