Gene

esrrgb

ID

ZDB-GENE-040616-4

Name

estrogen-related receptor gamma b

Symbol

esrrgb Nomenclature History

Previous Names

errb/g (1)
esrrgl
ERRbeta/gamma (1)
NR3B2/3 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Predicted to have several functions, including DNA-binding transcription factor activity; steroid hormone receptor activity; and zinc ion binding activity. Involved in otic vesicle development and otolith formation. Predicted to localize to nucleus. Orthologous to human ESRRG (estrogen related receptor gamma).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

8 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

ay556399 (7 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Tohmé et al., 2014
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With esrrgb Human Ortholog

No data available

Associated With esrrgb Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000536	Nuclear hormone receptor, ligand-binding domain
Domain	IPR001628	Zinc finger, nuclear hormone receptor-type
Family	IPR001723	Nuclear hormone receptor
Family	IPR024178	Estrogen receptor/oestrogen-related receptor
Family	IPR027289	Oestrogen-related receptor
Homologous_superfamily	IPR013088	Zinc finger, NHR/GATA-type
Homologous_superfamily	IPR035500	Nuclear hormone receptor-like domain superfamily