Gene
ift57
- ID
- ZDB-GENE-040614-1
- Name
- intraflagellar transport 57 homolog (Chlamydomonas)
- Symbol
- ift57 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Involved in several processes, including cilium organization; epithelial cilium movement involved in extracellular fluid movement; and photoreceptor cell maintenance. Predicted to localize to Golgi apparatus; intraciliary transport particle B; and microtubule organizing center. Human ortholog(s) of this gene implicated in orofaciodigital syndrome. Is expressed in head and retina. Orthologous to human IFT57 (intraflagellar transport 57).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907920 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 15 figures from 7 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| orofaciodigital syndrome XVIII | Alliance | ?Orofaciodigital syndrome XVIII | 617927 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Family | IPR019530 | Intra-flagellar transport protein 57 |
Domain Details Per Protein
| Protein | Length | Intra-flagellar transport protein 57 |
|---|---|---|
|
UniProtKB:Q6IVW0
|
407 |
Interactions and Pathways
No data available
Plasmids
No data available