Gene

ift57

ID
ZDB-GENE-040614-1
Name
intraflagellar transport 57 homolog (Chlamydomonas)
Symbol
ift57 Nomenclature History
Previous Names
  • curly (1)
  • hippi (1)
  • zgc:111831
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Acts upstream of or within several processes, including cilium organization; epithelial cilium movement involved in extracellular fluid movement; and photoreceptor cell maintenance. Predicted to be located in ciliary basal body. Predicted to be part of intraciliary transport particle B. Predicted to be active in Golgi apparatus; centrosome; and cilium. Is expressed in head and retina. Human ortholog(s) of this gene implicated in orofaciodigital syndrome. Orthologous to human IFT57 (intraflagellar transport 57).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
15 figures from 7 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ift57 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Orofaciodigital syndrome XVIII 617927
Associated With ift57 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR019530 Intra-flagellar transport protein 57
Domain Details Per Protein
Protein Length Intra-flagellar transport protein 57
UniProtKB:Q6IVW0 407
UniProtKB:B2GPW2 407
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-ift57 polyclonal Rabbit
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations