mos

ID

ZDB-GENE-040428-3

Name

MOS proto-oncogene, serine/threonine kinase

Symbol

mos Nomenclature History

Previous Names

c-mos (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable protein kinase activity. Predicted to be involved in negative regulation of metaphase/anaphase transition of meiotic cell cycle; positive regulation of MAPK cascade; and signal transduction. Predicted to be active in cytoplasm. Is expressed in blastomere and female organism. Orthologous to human MOS (MOS proto-oncogene, serine/threonine kinase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

7 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7152101 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mos Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Oocyte/zygote/embryo maturation arrest 20	620383

Associated With mos Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR008271	Serine/threonine-protein kinase, active site
Binding_site	IPR017441	Protein kinase, ATP binding site
Domain	IPR000719	Protein kinase domain
Family	IPR051681	Serine/Threonine Kinases and Pseudokinases
Homologous_superfamily	IPR011009	Protein kinase-like domain superfamily