ZFIN ID: ZDB-GENE-040426-847
Gene Name: histone deacetylase 3
Gene Symbol: hdac3    Nomenclature History

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Previous Name: zgc:55927 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 14 Mapping Details/Browsers
Description: Predicted to have chromatin binding activity; histone deacetylase activity; and transcription corepressor activity. Involved in several processes, including angiogenesis; liver development; and posterior lateral line development. Predicted to localize to cytoplasm; histone deacetylase complex; and transcription repressor complex. Is expressed in several structures, including axial blood vessel; blood vessel; digestive system; otic vesicle; and sensory system. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human HDAC3 (histone deacetylase 3).
Genome Resources: Alliance (1),  Gene:393965 (1),  Ensembl(GRCz11):ENSDARG00000037514 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hi2786aTg Transgenic Insertion Intron 1 Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22434 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35650 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hdac3 N/A 4
    MO2-hdac3 N/A 1
    MO3-hdac3 N/A 2
    DISEASE ASSOCIATED WITH hdac3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH hdac3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dorsal/ventral pattern formation (more)
    Cellular Component cytoplasm (more)
    Molecular Function chromatin binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript hdac3-202 (1)    Ensembl 705
    mRNA hdac3-201 (1)    Ensembl 2138
    ottdart00000032801 (1) 2135
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM hdac3 No data available
    MARKER RELATIONSHIPS
    hdac3 Contained in: [BAC] CH211-194M19 (1)
    [PAC] BUSM1-87D10 (1)
    hdac3 Encodes: [cDNA] MGC:55927 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_200990 (1) 2069 nt
    Genomic GenBank:BX927254 (1) 152687 nt
    Select Tool
    Polypeptide UniProtKB:F1RCG9 (1) 428 aa
    Sequence Information (all 12)
    ORTHOLOGY for hdac3 ( Chr: 14 )
    CITATIONS (50)