ZFIN ID: ZDB-GENE-040426-741
Gene Name: RNA binding protein, mRNA processing factor 2b
Gene Symbol: rbpms2b    Nomenclature History

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Previous Names: rbpms2, Hermes (1), zgc:55559 (1), zgc:77170 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits mRNA binding activity. Involved in dendrite morphogenesis; regulation of retinal ganglion cell axon guidance; and retinal ganglion cell axon guidance. Is expressed in several structures, including cardiovascular system; gonad; optic vesicle; retina; and ventral mesoderm. Orthologous to human RBPMS2 (RNA binding protein, mRNA processing factor 2).
Genome Resources: Alliance (1),  Gene:393229 (1),  Ensembl(GRCz11):ENSDARG00000079578 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ae32 Insertion Unknown Unknown CRISPR
sa9329 Point Mutation Unknown Splice Site, Exon Loss of Exon 3 ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18890 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tpl96Gt Transgenic Insertion Unknown Unknown DNA
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-rbpms2b 1
    MO1-rbpms2b N/A 2
    MO2-rbpms2b N/A 2
    PHENOTYPE
    Data: Fig. 3 from Kaufman et al., 2018
    Observed in:
    DISEASE ASSOCIATED WITH rbpms2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH rbpms2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dendrite morphogenesis (more)
    Molecular Function mRNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Domain IPR000504 RNA recognition motif domain
    Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
    Domain IPR034787 RBPMS2, RNA recognition motif
    Homologous_superfamily IPR035979 RNA-binding domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    aberrant processed transcript rbpms2b-202 (1)    Ensembl 768
    mRNA rbpms2b-201 (1)    Ensembl 1911
    rbpms2b-206 (1)    Ensembl 764
    rbpms2b-207 (1)    Ensembl 871
    rbpms2b-208 (1)    Ensembl 317
    ncRNA rbpms2b-005 (1)    Ensembl 730
    rbpms2b-006 (1)    Ensembl 502
    rbpms2b-008 (1)    Ensembl 832
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-rbpms2 polyclonal Rabbit IHC 5
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rbpms2b
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    tg(buc:mapple-rbpms2b) buc mApplerbpms2b Danio rerio 1 1
    tg2(buc:mapple-rbpms2b) buc mApplerbpms2b Danio rerio 1 1
    MARKER RELATIONSHIPS
    rbpms2b Contained in: [BAC] CH211-231O17 (1), DKEY-24M14 (1) (order this)
    rbpms2b Encodes: [cDNA] MGC:55559 (1), MGC:77170
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200259 (1) 1901 bp
    Genomic GenBank:BX663612 (1) 181415 bp
    Select Tool
    Polypeptide UniProtKB:Q7ZUL7 (1) 200 aa
    Sequence Information (all 22)
    ORTHOLOGY for rbpms2b ( Chr: 7 )
    CITATIONS (38)