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ZIRC
ZFIN ID: ZDB-GENE-040426-2656
Gene Name: dopa decarboxylase
Gene Symbol: ddc
Sequence Ontology ID : SO:0000704

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Previous Names: aromatic amino acid decarboxylase (1), wu:fa56d05, wu:fd59h03, wu:fk20h01, zgc:65801 (1), zgc:76929 (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have carboxy-lyase activity and pyridoxal phosphate binding activity. Involved in brain development. Human ortholog(s) of this gene implicated in Parkinson's disease; aromatic L-amino  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa36042 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH ddc HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    aromatic L-amino acid decarboxylase deficiency Aromatic L-amino acid decarboxylase deficiency 608643
    DISEASE ASSOCIATED WITH ddc VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process brain development (more)
    Cellular Component cellular_component (more)
    Molecular Function carboxy-lyase activity (more)
    GO Terms (all 8)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA ddc-002 (1) 814
    mRNA ddc-201 (1) 4117
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ddc No data available
    MARKER RELATIONSHIPS
    ddcContained in: [BAC] CH211-149M3 (1) (order this)
    ddcContains: [STS] chunp30644
    ddcEncodes: [EST] fa56d05 (1), fd59h03 (1), fk20h01 (1)
    [cDNA] MGC:65801 (1) (order this), MGC:76929 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_213342 (1) 4136bp
    Genomic GenBank:CR478208 (1) 195111bp
    Select Tool
    Polypeptide UniProtKB:Q7SZR0 (1) 480aa
    Sequence Clusters UniGene:75993 (1)
    Sequence Information (all 17)
    ORTHOLOGY for ddc (Chr: 16)
    CITATIONS (35)