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ZIRC
ZFIN ID: ZDB-GENE-040426-2575
Gene Name: catenin, beta 2
Gene Symbol: ctnnb2
Sequence Ontology ID : SO:0000704

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Previous Names: ich, wu:fa12h09, wu:fc16f05, zgc:65770

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(Including Attributions)
Location: Chr: 19 Mapping Details/Browsers
Nomenclature History
Note:
AUTOMATED DESCRIPTION
Predicted to have several functions, including alpha-catenin binding activity; cadherin binding activity; and transcription coactivator activity. Involved in canonical Wnt signaling pathway;  ...
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ctnnb2_unspecified Unspecified Unknown Unknown
p1 Unknown Unknown Unknown
sa23605 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43353 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    DISEASE ASSOCIATED WITH ctnnb2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant non-syndromic intellectual disability 19 Neurodevelopmental disorder with spastic diplegia and visual defects 615075
    colorectal cancer Colorectal cancer, somatic 114500
    exudative vitreoretinopathy 7 Exudative vitreoretinopathy 7 617572
    hepatocellular carcinoma Hepatocellular carcinoma, somatic 114550
    medulloblastoma Medulloblastoma, somatic 155255
    ovarian cancer Ovarian cancer, somatic 167000
    pilomatrixoma Pilomatricoma, somatic 132600
    DISEASE ASSOCIATED WITH ctnnb2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process canonical Wnt signaling pathway (more)
    Cellular Component nucleus (more)
    Molecular Function protein binding (more)
    GO Terms (all 17)
    TRANSCRIPTS No data available
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ctnnb2
    MARKER RELATIONSHIPS
    ctnnb2Contains: [SNP] rs3729004 (1), rs3729005 (1), rs3729006 (1)
    ctnnb2Encodes: [EST] fa12h09 (1), fc16f05
    [cDNA] MGC:65770 (1) (order this)
    ctnnb2Has Artifact: [EST] fd20a06 (1)
    [cDNA] MGC:56232 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001889 (1) 3550bp
    Polypeptide UniProtKB:E7FC99 (1) 778aa
    Sequence Clusters UniGene:29035 (1)
    Sequence Information (all 21)
    OTHER ctnnb2 GENE PAGES
  • Alliance (1)
  • Gene:324004 (1)
  • Ensembl(GRCz11):ENSDARG00000023472 (2)
  • ORTHOLOGY for ctnnb2 (Chr: 19)
    CITATIONS (71)