Gene
rbfox2
- ID
- ZDB-GENE-040426-2464
- Name
- RNA binding fox-1 homolog 2
- Symbol
- rbfox2 Nomenclature History
- Previous Names
-
- rbm9
- zgc:85694
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable mRNA binding activity. Acts upstream of or within regulation of RNA splicing and striated muscle tissue development. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including muscle; pectoral fin bud; segmental plate; skeletal muscle satellite cell; and tail bud. Human ortholog(s) of this gene implicated in congenital heart disease. Orthologous to human RBFOX2 (RNA binding fox-1 homolog 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Martin et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR025670 | Fox-1 C-terminal domain |
| Domain | IPR034237 | FOX1, RNA recognition motif |
| Family | IPR017325 | RNA binding protein fox-1 homolog 1-3 |
| Family | IPR047131 | RNA binding protein fox-1 homolog 1-like |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Length | Fox-1 C-terminal domain | FOX1, RNA recognition motif | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA binding protein fox-1 homolog 1-3 | RNA binding protein fox-1 homolog 1-like | RNA recognition motif domain |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A0A8M9Q615
|
358 | |||||||
|
UniProtKB:A0A8M9PZL7
|
392 | |||||||
|
UniProtKB:Q6NV06
|
241 | |||||||
|
UniProtKB:A0A8M9QFB1
|
247 | |||||||
|
UniProtKB:A0A8M9PM01
|
425 | |||||||
|
UniProtKB:A0A8M9QA95
|
425 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
rbfox2-201
(1)
|
Ensembl | 3,274 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-rbfox2 | polyclonal | Rabbit |
|
3 |
Plasmids