ZFIN is now using GRCz12tu for Genomic Data
Gene
cldn5a
- ID
- ZDB-GENE-040426-2442
- Name
- claudin 5a
- Symbol
- cldn5a Nomenclature History
- Previous Names
-
- cldn5
- zgc:85723
- Type
- protein_coding_gene
- Location
- Chr: 8 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable structural molecule activity. Acts upstream of or within Kupffer's vesicle development; determination of heart left/right asymmetry; and establishment of endothelial barrier. Located in apical junction complex. Is expressed in several structures, including central nervous system; hyaloid vessel; immature eye; neural tube; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CLDN5 (claudin 5).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 18 figures from 11 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:85723 (21 images)
Wild Type Expression Summary
- All Phenotype Data
- 16 figures from 5 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Claudin | Claudin, conserved site | PMP-22/EMP/MP20/Claudin |
|---|---|---|---|---|---|
| UniProtKB:Q6NUZ6 | InterPro | 215 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cldn5a-201
(1)
|
Ensembl | 1,557 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-cldn5 | monoclonal | IgG1 | Mouse |
|
Life Technologies (Invitrogen)
|
26 |
Plasmids
No data available
- Genome Browsers