Gene

cldn5a

ID
ZDB-GENE-040426-2442
Name
claudin 5a
Symbol
cldn5a Nomenclature History
Previous Names
  • cldn5
  • zgc:85723
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have structural molecule activity. Involved in Kupffer's vesicle development; determination of heart left/right asymmetry; and establishment of endothelial barrier. Localizes to apical junction complex. Is expressed in several structures, including central nervous system; hyaloid vessel; immature eye; neural tube; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human CLDN5 (claudin 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cldn5a Human Ortholog
No data available
Associated With cldn5a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017974 Claudin, conserved site
Family IPR004031 PMP-22/EMP/MP20/Claudin superfamily
Family IPR006187 Claudin
Domain Details Per Protein
Protein Length Claudin Claudin, conserved site PMP-22/EMP/MP20/Claudin superfamily
UniProtKB:Q6NUZ6 215
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cldn5 monoclonal IgG1 Mouse
  • IHC
Life Technologies (Invitrogen)
14
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations