Gene

tdrd7a

ID

ZDB-GENE-040426-2103

Name

tudor domain containing 7 a

Symbol

tdrd7a Nomenclature History

Previous Names

tdrd7
si:ch211-288h2.2
wu:fi12c12
zgc:56669 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to have mRNA binding activity. Involved in P granule organization. Localizes to P granule. Human ortholog(s) of this gene implicated in cataract 36. Is expressed in blastodisc; blastomere; and primordial germ cell. Orthologous to human TDRD7 (tudor domain containing 7).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

9 figures from 4 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:56669 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Strasser et al., 2008
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tdrd7a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
cataract 36	Alliance	Cataract 36	613887

Associated With tdrd7a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002999	Tudor domain
Domain	IPR025605	OST-HTH/LOTUS domain
Domain	IPR037978	TDRD7, third LOTUS domain
Domain	IPR047448	TDRD7, second Tudor domain
Domain	IPR047449	TDRD7, third Tudor domain
Family	IPR050621	Tudor domain-containing
Homologous_superfamily	IPR035437	SNase-like, OB-fold superfamily
Homologous_superfamily	IPR041966	LOTUS-like domain