Gene
wdr24
- ID
- ZDB-GENE-040426-2012
- Name
- WD repeat domain 24
- Symbol
- wdr24 Nomenclature History
- Previous Names
-
- wu:fd05f12
- zgc:55946 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to be involved in cellular response to amino acid starvation; positive regulation of TORC1 signaling; and positive regulation of macroautophagy. Predicted to act upstream of or within autophagy and positive regulation of TOR signaling. Predicted to be located in lysosomal membrane. Predicted to be part of GATOR2 complex. Predicted to be active in cytosol and vacuolar membrane. Orthologous to human WDR24 (WD repeat domain 24).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:55946 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR019775 | WD40 repeat, conserved site |
| Family | IPR037590 | GATOR2 complex protein WDR24 |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | GATOR2 complex protein WDR24 | WD40 repeat | WD40 repeat, conserved site | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|
|
UniProtKB:Q7ZVL2
|
779 | |||||
|
UniProtKB:A0A8M2B9U3
|
778 |
Interactions and Pathways
No data available
Plasmids
No data available