Gene

cadm2a

ID
ZDB-GENE-040426-1614
Name
cell adhesion molecule 2a
Symbol
cadm2a Nomenclature History
Previous Names
  • igsf4d (1)
  • zgc:66339 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in astrocytoma; autism spectrum disorder; obesity; psoriasis; and type 2 diabetes mellitus. Is expressed in immature eye; nervous system; and pancreatic system. Orthologous to human CADM2 (cell adhesion molecule 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
12 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cadm2a Human Ortholog
No data available
Associated With cadm2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR003006 Immunoglobulin/major histocompatibility complex, conserved site
Domain IPR003585 Neurexin/syndecan/glycophorin C
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Domain IPR013106 Immunoglobulin V-set domain
Domain IPR013162 CD80-like, immunoglobulin C2-set
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length CD80-like, immunoglobulin C2-set Immunoglobulin domain subtype Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin/major histocompatibility complex, conserved site Immunoglobulin subtype 2 Immunoglobulin V-set domain Neurexin/syndecan/glycophorin C
UniProtKB:A0A8M9PTN6 436
UniProtKB:A0A8M9Q678 433
UniProtKB:Q6PFK4 405
UniProtKB:A0A8M2B1G4 427
UniProtKB:A0A8M2B1M0 442
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA cadm2a-201 (1) Ensembl 1,748 nt
mRNA cadm2a-202 (1) Ensembl 994 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cadm2a polyclonal Rabbit
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations