Gene
slc25a39
- ID
- ZDB-GENE-040426-1250
- Name
- solute carrier family 25 member 39
- Symbol
- slc25a39 Nomenclature History
- Previous Names
-
- zgc:63736
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to enable 2 iron, 2 sulfur cluster binding activity and metallochaperone activity. Acts upstream of or within heme biosynthetic process. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Is expressed in intermediate cell mass of mesoderm and nucleate erythrocyte. Orthologous to human SLC25A39 (solute carrier family 25 member 39).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63736 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Nilsson et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitochondrial carrier domain superfamily | Mitochondrial carrier protein | Mitochondrial carrier protein Mtm1-like | Mitochondrial substrate/solute carrier |
|---|---|---|---|---|---|---|
| UniProtKB:A0A8M2BB41 | InterPro | 342 | ||||
| UniProtKB:A0A8M2BB72 | InterPro | 341 | ||||
| UniProtKB:Q7SXW0 | InterPro | 359 | ||||
| UniProtKB:A0A8M2BBF8 | InterPro | 358 | ||||
| UniProtKB:F1QVQ4 | InterPro | 359 |
1 - 5 of 5
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc25a39-201
(1)
|
Ensembl | 2,063 nt | ||
| mRNA |
slc25a39-202
(1)
|
Ensembl | 650 nt | ||
| mRNA |
slc25a39-203
(1)
|
Ensembl | 652 nt |
1 - 3 of 3
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-151M15 | ZFIN Curated Data | |
| Encodes | cDNA | MGC:63736 | ZFIN Curated Data |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_200486 (1) | 2075 nt | ||
| Genomic | GenBank:BX901883 (1) | 241961 nt | ||
| Polypeptide | UniProtKB:F1QVQ4 (1) | 359 aa |
- Wang, Y., Liu, X., Xie, B., Yuan, H., Zhang, Y., Zhu, J. (2019) The NOTCH1-dependent HIF1α/VGLL4/IRF2BP2 oxygen sensing pathway triggers erythropoiesis terminal differentiation. Redox Biology. 28:101313
- Foulkes, M.J., Henry, K.M., Rougeot, J., Hooper-Greenhill, E., Loynes, C.A., Jeffrey, P., Fleming, A., Savage, C.O., Meijer, A.H., Jones, S., Renshaw, S.A. (2017) Expression and regulation of drug transporters in vertebrate neutrophils. Scientific Reports. 7:4967
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Nilsson, R., Schultz, I.J., Pierce, E.L., Soltis, K.A., Naranuntarat, A., Ward, D.M., Baughman, J.M., Paradkar, P.N., Kingsley, P.D., Culotta, V.C., Kaplan, J., Palis, J., Paw, B.H., and Mootha, V.K. (2009) Discovery of genes essential for heme biosynthesis through large-scale gene expression analysis. Cell Metabolism. 10(2):119-130
- Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903
1 - 5 of 5
Show