Gene

eif2b3

ID
ZDB-GENE-040426-1039
Name
eukaryotic translation initiation factor 2B, subunit 3 gamma
Symbol
eif2b3 Nomenclature History
Previous Names
  • zgc:56473 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have guanyl-nucleotide exchange factor activity and translation initiation factor activity. Predicted to be involved in cytoplasmic translational initiation. Predicted to localize to eukaryotic translation initiation factor 2B complex and guanyl-nucleotide exchange factor complex. Is expressed in eye and gut. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter. Orthologous to human EIF2B3 (eukaryotic translation initiation factor 2B subunit gamma).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eif2b3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
leukoencephalopathy with vanishing white matter Alliance Leukoencephalopathy with vanishing white matter 603896
Associated With eif2b3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005835 Nucleotidyl transferase domain
Homologous_superfamily IPR029044 Nucleotide-diphospho-sugar transferases
Domain Details Per Protein
Protein Length Nucleotide-diphospho-sugar transferases Nucleotidyl transferase domain
UniProtKB:Q7ZTY5 453
UniProtKB:E9QG01 170
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations