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Phenotype Figure Summary
Marker:
eif2b3
Conditions:
Standard or Control
Publication
Data
Fish
Anatomy
Kim
et al.
, 2021
Fig. S2
eif2b3
ck156a/ck156a
midbrain hindbrain boundary
psat1
expression increased amount, abnormal
midbrain hindbrain boundary
xbp1
expression increased amount, abnormal
Fig. S3
eif2b3
ck156a/ck156a
midbrain hindbrain boundary
atf4a
expression increased amount, abnormal
midbrain hindbrain boundary
atf6
expression increased amount, abnormal
Fig. S4
eif2b3
ck156a/ck156a
lens decreased size, abnormal
Figure 1
eif2b3
ck156a/ck156a
, 
eif2b3
ck156a/ck156a
; ck5Tg
central nervous system glial cell (sensu Vertebrata)
olig2
expression decreased amount, abnormal
midbrain neuronal stem cell
nes
expression increased amount, abnormal
myelination disrupted, abnormal
nervous system myelin sheath
mbpa
expression decreased amount, abnormal
Figure 4
eif2b3
ck156a/ck156a
midbrain hindbrain boundary
abat
expression increased amount, abnormal
midbrain hindbrain boundary
ass1
expression decreased amount, abnormal
midbrain hindbrain boundary
cad
expression decreased amount, abnormal
midbrain hindbrain boundary
lonp1
expression increased amount, abnormal
midbrain hindbrain boundary
septin6
expression decreased amount, abnormal
midbrain hindbrain boundary
slc1a4
expression increased amount, abnormal
Lee
et al.
, 2021
Fig. 1
eif2b3
ck156a/ck156a
eye decreased size, abnormal
heart edematous, abnormal
whole organism dead, abnormal
whole organism decreased life span, abnormal
Fig. 2
eif2b3
ck156a/ck156a
, 
eif2b3
ck156a/ck156a
; ck1Tg
cranial ganglion
mbpa
expression decreased amount, abnormal
myelination of posterior lateral line nerve axons disrupted, abnormal
oligodendrocyte myelination disrupted, abnormal
posterior lateral line nerve
mbpa
expression decreased amount, abnormal
Fig. 3
eif2b3
ck156a/ck156a
eye monocyte increased amount, abnormal
forebrain
olig2
expression decreased amount, abnormal
microglia differentiation disrupted, abnormal
microglial cell
apoeb
expression decreased amount, abnormal
microglial cell decreased amount, abnormal
midbrain monocyte increased amount, abnormal
retina
olig2
expression decreased amount, abnormal
Fig. 4
eif2b3
ck156a/ck156a
; s843Tg
, 
eif2b3
ck156a/ck156a
midbrain
vegfaa
expression increased amount, abnormal
midbrain cranial vasculature increased branchiness, abnormal
pharyngeal vasculature increased diameter, abnormal
Fig. S2
eif2b3
ck156a/ck156a
forebrain
olig2
expression decreased amount, abnormal
retina
olig2
expression decreased amount, abnormal
Fig. S3
eif2b3
ck156a/ck156a
; s843Tg
cranial vasculature angiogenesis increased occurrence, abnormal
cranial vasculature increased branchiness, abnormal
intersegmental vessel angiogenesis increased occurrence, abnormal
subintestinal vein angiogenesis increased occurrence, abnormal
Fig. S4
eif2b3
ck156a/ck156a
brain
tp53
expression increased amount, abnormal
intestine
atf6
expression increased amount, abnormal
intestine
xbp1
expression increased amount, abnormal
liver
atf6
expression increased amount, abnormal
liver
xbp1
expression increased amount, abnormal
pancreas
atf6
expression increased amount, abnormal
pancreas
xbp1
expression increased amount, abnormal
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