Gene

dtnbp1a

ID
ZDB-GENE-040426-1036
Name
dystrobrevin binding protein 1a
Symbol
dtnbp1a Nomenclature History
Previous Names
  • dtnbp1
  • hps7 (1)
  • zgc:56462 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Involved in several processes, including anterograde synaptic vesicle transport; platelet dense granule organization; and regulation of synaptic vesicle exocytosis. Predicted to be located in several cellular components, including cytoplasmic vesicle membrane; endoplasmic reticulum; and postsynaptic density. Predicted to be part of BLOC-1 complex. Is expressed in several structures, including epidermis; neural crest; periderm; pigment cell; and retina. Used to study Hermansky-Pudlak syndrome. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 7 and schizophrenia. Orthologous to human DTNBP1 (dystrobrevin binding protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Chen et al., 2018
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dtnbp1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Hermansky-Pudlak syndrome 7 Alliance Hermansky-Pudlak syndrome 7 614076
Associated With dtnbp1a Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR007531 Dysbindin
Domain Details Per Protein
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations