Gene

per1b

ID

ZDB-GENE-040419-1

Name

period circadian clock 1b

Symbol

per1b Nomenclature History

Previous Names

per4
zfper4 (1)

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Predicted to have transcription corepressor binding activity and transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including generation of neurons; retina development in camera-type eye; and visual perception. Predicted to localize to cytoplasm and nucleus. Used to study attention deficit hyperactivity disorder. Is expressed in several structures, including heart; liver; muscle; ovary; and retina. Orthologous to human PER1 (period circadian regulator 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

35 figures from 22 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 10 figures from 4 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With per1b Human Ortholog

No data available

Associated With per1b Via Experimental Models

Human Disease	Fish	Conditions	Citations
attention deficit hyperactivity disorder	per1b^{sus001Tg/sus001Tg}	standard conditions	Huang et al., 2015
attention deficit hyperactivity disorder	per1b^{sus001Tg/sus001Tg} (AB)	standard conditions	Nie et al., 2017

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR013655	PAS fold-3
Domain	IPR022728	Period circadian-like, C-terminal
Domain	IPR048814	Period circadian protein homolog 1-3, PAS-A domain
Family	IPR050760	Period circadian regulator
Homologous_superfamily	IPR035965	PAS domain superfamily