Gene

mnx2b

ID
ZDB-GENE-040415-2
Name
motor neuron and pancreas homeobox 2b
Symbol
mnx2b Nomenclature History
Previous Names
  • mnr2b (1)
  • hlxb9lb (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity. Involved in spinal cord motor neuron cell fate specification. Predicted to localize to nucleus. Is expressed in several structures, including endodermal cell; lateral mesoderm; motor neurons; spinal cord; and spinal cord neural tube.
Genome Resources
Note
The name of this gene was changed from hlxb9lb to mnx2b to more accurately reflect its relationship to the MNX family of genes.
Comparative Information
Expression
All Expression Data
6 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from See et al., 2014
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mnx2b Human Ortholog
No data available
Associated With mnx2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeodomain
Domain IPR020479 Homeodomain, metazoa
Family IPR042768 Homeobox protein MNX1/Ceh-12
Homologous_superfamily IPR009057 Homedomain-like superfamily
Domain Details Per Protein
Protein Length Homedomain-like superfamily Homeobox, conserved site Homeobox protein MNX1/Ceh-12 Homeodomain Homeodomain, metazoa
UniProtKB:F1RCJ6 328
UniProtKB:A2CEW5 320
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mnx2b-201 (1) Ensembl 1,031 nt
mRNA mnx2b-202 (1) Ensembl 1,152 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations