Gene
eif4ea
- ID
- ZDB-GENE-040413-1
- Name
- eukaryotic translation initiation factor 4ea
- Symbol
- eif4ea Nomenclature History
- Previous Names
-
- eif4E-1A (1)
- eif4e1a
- eif4e
- zgc:86680
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Exhibits RNA 7-methylguanosine cap binding activity and translation initiation factor activity. Involved in translational initiation. Localizes to cytoplasm and nucleus. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human EIF4E (eukaryotic translation initiation factor 4E).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {Autism, susceptibility to, 19} | 615091 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Eukaryotic translation initiation factor 4E (eIF-4E), conserved site | Translation Initiation factor eIF- 4e | Translation Initiation factor eIF- 4e-like |
|---|---|---|---|---|
|
UniProtKB:Q9DFS6
|
215 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
eif4ea-201
(1)
|
Ensembl | 1,484 nt | ||
| ncRNA |
eif4ea-002
(1)
|
Ensembl | 590 nt | ||
| ncRNA |
eif4ea-003
(1)
|
Ensembl | 730 nt |
Interactions and Pathways
No data available
Plasmids
No data available