Gene

crim1

ID
ZDB-GENE-040312-2
Name
cysteine rich transmembrane BMP regulator 1 (chordin-like)
Symbol
crim1 Nomenclature History
Previous Names
  • wu:fc29f08
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Predicted to have insulin-like growth factor binding activity and serine-type endopeptidase inhibitor activity. Involved in blood vessel development; notochord morphogenesis; and somitogenesis. Predicted to localize to extracellular region and integral component of membrane. Is expressed in several structures, including axis; intermediate cell mass of mesoderm; notochord; otic vesicle; and posterior segment eye. Used to study cataract and microphthalmia. Orthologous to human CRIM1 (cysteine rich transmembrane BMP regulator 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Brastrom et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With crim1 Human Ortholog
No data available
Associated With crim1 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000867 Insulin-like growth factor-binding protein, IGFBP
Domain IPR001007 VWFC domain
Domain IPR004094 Antistasin-like domain
Homologous_superfamily IPR009030 Growth factor receptor cysteine-rich domain superfamily
Homologous_superfamily IPR011061 Hirudin/antistatin
Domain Details Per Protein
Protein Length Antistasin-like domain Growth factor receptor cysteine-rich domain superfamily Hirudin/antistatin Insulin-like growth factor-binding protein, IGFBP VWFC domain
UniProtKB:B3DH05 1027
UniProtKB:Q7T3Q2 1027
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations