ZFIN ID: ZDB-GENE-040122-5
Gene Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a
Gene Symbol: ywhaqa    Nomenclature History

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Previous Names: ywhaq2 (1), ywhaq

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 20 Mapping Details/Browsers
Description: Predicted to have monooxygenase activity and protein domain specific binding activity. Predicted to be involved in oxidation-reduction process. Is expressed in several structures, including immature eye; liver; nervous system; otic vesicle; and tail bud. Human ortholog(s) of this gene implicated in transitional cell carcinoma and vulva squamous cell carcinoma. Orthologous to several human genes including YWHAQ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta).
Genome Resources: Alliance (1),  Gene:399487 (1),  Ensembl(GRCz11):ENSDARG00000042539 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021521Tg Transgenic Insertion Unknown Unknown DNA
sa1704 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa10800 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ywhaqa HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ywhaqa VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process oxidation-reduction process (more)
    Molecular Function monooxygenase activity (more)
    GO Terms (all 3)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ywhaqa-201 (1)    Ensembl 1959
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ywhaqa No data available
    MARKER RELATIONSHIPS
    ywhaqa Contained in: [BAC] DKEY-81B15 (1) (order this)
    ywhaqa Encodes: [cDNA] MGC:55959 (1), MGC:77161 (1), MGC:174433 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_201513 (1) 1958 nt
    Genomic GenBank:BX248136 (1) 222316 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q7ZUM0 (1) 245 aa
    Sequence Information (all 16)
    ORTHOLOGY for ywhaqa ( Chr: 20 )
    CITATIONS (35)