Gene

bmi1b

ID
ZDB-GENE-040116-4
Name
bmi1 polycomb ring finger oncogene 1b
Symbol
bmi1b Nomenclature History
Previous Names
  • pcgf4b
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to have promoter-specific chromatin binding activity. Involved in cerebellum development. Predicted to localize to PRC1 complex. Human ortholog(s) of this gene implicated in acute myeloid leukemia; colorectal carcinoma; and hepatocellular carcinoma. Orthologous to several human genes including COMMD3-BMI1 (COMMD3-BMI1 readthrough).
Genome Resources
Note
None
Expression
All Expression Data
2 figures from Dupret et al., 2016
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bmi1b Human Ortholog
No data available
Associated With bmi1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017907 Zinc finger, RING-type, conserved site
Domain IPR001841 Zinc finger, RING-type
Domain IPR032443 RAWUL domain
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length RAWUL domain Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type Zinc finger, RING-type, conserved site
UniProtKB:B0UXV8 326
UniProtKB:Q7T3E6 324
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations