Gene

taf12

ID

ZDB-GENE-031030-5

Name

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor

Symbol

taf12 Nomenclature History

Previous Names

fl03a12
wu:fl03a12 (1)

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to enable DNA binding activity and TBP-class protein binding activity. Predicted to be involved in RNA polymerase II preinitiation complex assembly. Predicted to act upstream of or within DNA-templated transcription initiation. Predicted to be located in nucleus. Predicted to be part of transcription factor TFIID complex. Orthologous to human TAF12 (TATA-box binding protein associated factor 12).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:65846 (1 image)
IMAGE:3712079 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

No data available

Sequence Targeting Reagents

No data available

Human Disease

Associated With taf12 Human Ortholog

No data available

Associated With taf12 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003228	Transcription initiation factor TFIID subunit 12 domain
Family	IPR037794	Transcription initiation factor TFIID subunit 12
Homologous_superfamily	IPR009072	Histone-fold

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Domain Details Per Protein

Protein	Additional Resources	Length	Histone-fold	Transcription initiation factor TFIID subunit 12	Transcription initiation factor TFIID subunit 12 domain
UniProtKB:Q6P013	InterPro	162

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Transcripts

Genome Browsers

Genome Build: GRCz11Chromosome: 16

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	taf12-201 (1) Ensembl	Ensembl	769 nt	Select Tool ZFIN BLAST
mRNA	taf12-203 (1) Ensembl	Ensembl	1,473 nt	Select Tool ZFIN BLAST
mRNA	taf12-204 (1) Ensembl	Ensembl	902 nt	Select Tool ZFIN BLAST
ncRNA	taf12-004 (1) Ensembl	Ensembl	714 nt	Select Tool ZFIN BLAST

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Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

No data available

Marker Relationships

Relationship	Marker Type	Marker	Accession Numbers	Citations
Contained in	BAC	DKEY-34D22	CR936484	ZFIN Curated Data
Encodes	EST	fl03a12	BE201914	ZFIN Curated Data
Encodes	EST	IMAGE:3712079	CB354618	Thisse et al., 2004
Encodes	cDNA	MGC:56398	BC050160	ZFIN Curated Data
Encodes	cDNA	MGC:65846	BC056696	ZFIN Curated Data
Encodes	cDNA	MGC:77850	BC065878	ZFIN Curated Data
Encodes	cDNA	MGC:173932	BC152198	ZFIN Curated Data

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Sequences

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:NM_198368 (1)	1480 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:CR936200 (1)	154978 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q6P013 (1)	162 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Species	Symbol	Chromosome	Accession #	Evidence
Human	TAF12	1	Ensembl:ENSG00000120656 Gene:6883 HGNC:11545 OMIM:600773	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)
Mouse	Taf12	4	Ensembl:ENSMUSG00000028899 Gene:66464 MGI:1913714	Amino acid sequence comparison (1) Conserved genome location (synteny) (1)

Citations

Include unpublished citations

Strausberg,R.L., Feingold,E.A., Grouse,L.H., Derge,J.G., Klausner,R.D., Collins,F.S., Wagner,L., Shenmen,C.M., Schuler,G.D., Altschul,S.F., Zeeberg,B., Buetow,K.H., Schaefer,C.F., Bhat,N.K., Hopkins,R.F., Jordan,H., Moore,T., Max,S.I., Wang,J., Hsieh,F., Diatchenko,L., Marusina,K., Farmer,A.A., Rubin,G.M., Hong,L., Stapleton,M., Soares,M.B., Bonaldo,M.F., Casavant,T.L., Scheetz,T.E., Brownstein,M.J., Usdin,T.B., Toshiyuki,S., Carninci,P., Prange,C., Raha,S.S., Loquellano,N.A., Peters,G.J., Abramson,R.D., Mullahy,S.J., Bosak,S.A., McEwan,P.J., McKernan,K.J., Malek,J.A., Gunaratne,P.H., Richards,S., Worley,K.C., Hale,S., Garcia,A.M., Gay,L.J., Hulyk,S.W., Villalon,D.K., Muzny,D.M., Sodergren,E.J., Lu,X., Gibbs,R.A., Fahey,J., Helton,E., Ketteman,M., Madan,A., Rodrigues,S., Sanchez,A., Whiting,M., Madan,A., Young,A.C., Shevchenko,Y., Bouffard,G.G., Blakesley,R.W., Touchman,J.W., Green,E.D., Dickson,M.C., Rodriguez,A.C., Grimwood,J., Schmutz,J., Myers,R.M., Butterfield,Y.S., Krzywinski,M.I., Skalska,U., Smailus,D.E., Schnerch,A., Schein,J.E., Jones,S.J., and Marra,M.A. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proceedings of the National Academy of Sciences of the United States of America. 99(26):16899-903

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