Gene

ddx49

ID
ZDB-GENE-031030-3
Name
DEAD (Asp-Glu-Ala-Asp) box polypeptide 49
Symbol
ddx49 Nomenclature History
Previous Names
  • wu:fb82g04 (1)
  • wu:fd12e05
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to enable several functions, including ATP binding activity; RNA helicase activity; and nucleic acid binding activity. Predicted to be involved in rRNA processing. Predicted to be active in nucleus. Is expressed in female organism. Orthologous to human DDX49 (DEAD-box helicase 49).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
sa4404Allele with one point mutationUnknownPremature StopENU
sa24887Allele with one point mutationUnknownSplice SiteENU
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Sequence Targeting Reagents
No data available
Human Disease
Associated With ddx49 Human Ortholog
No data available
Associated With ddx49 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site
Domain IPR001650 Helicase, C-terminal domain-like
Domain IPR011545 DEAD/DEAH box helicase domain
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR014014 RNA helicase, DEAD-box type, Q motif
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Domain Details Per Protein
Protein Additional Resources Length ATP-dependent RNA helicase DEAD-box, conserved site DEAD box RNA helicase DEAD/DEAH box helicase domain Helicase, C-terminal domain-like Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase RNA helicase, DEAD-box type, Q motif
UniProtKB:Q7ZUT9 InterPro 468
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 11
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ddx49-201 (1) Ensembl 1,632 nt
mRNA ddx49-203 (1) Ensembl 799 nt
ncRNA ddx49-003 (1) Ensembl 604 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-255D18ZFIN Curated Data
EncodesESTfb82g04ZFIN Curated Data
EncodesESTfd12e05
EncodescDNAMGC:56128ZFIN Curated Data
EncodescDNAMGC:86694ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanDDX4919
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
MouseDdx498
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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