ZFIN is now using GRCz12tu for Genomic Data
Gene
fscn1a
- ID
- ZDB-GENE-031009-1
- Name
- fascin actin-bundling protein 1a
- Symbol
- fscn1a Nomenclature History
- Previous Names
-
- fscn1
- sb:cb589
- zgc:153632
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables actin filament binding activity; protein-macromolecule adaptor activity; and signaling receptor binding activity. Acts upstream of or within several processes, including embryonic viscerocranium morphogenesis; epiboly; and neural crest cell migration involved in sympathetic nervous system development. Predicted to be located in cell leading edge and cytoskeleton. Predicted to be active in several cellular components, including actin-based cell projection; lamellipodium; and ruffle. Is expressed in several structures, including head; mesoderm; nervous system; neural crest; and neural plate. Orthologous to human FSCN1 (fascin actin-bundling protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 10 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb589 (18 images)
Wild Type Expression Summary
- All Phenotype Data
- 20 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Actin-crosslinking | Fascin | Fascin-like domain | Fascin, metazoans |
|---|---|---|---|---|---|---|
| UniProtKB:Q08C47 | InterPro | 491 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
fscn1a-201
(1)
|
Ensembl | 3,077 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-fscn1 | monoclonal | IgG | Rabbit |
|
Epitomics, Inc
|
3 |
Plasmids
No data available
- Genome Browsers