Gene

fscn1a

ID
ZDB-GENE-031009-1
Name
fascin actin-bundling protein 1a
Symbol
fscn1a Nomenclature History
Previous Names
  • fscn1
  • sb:cb589
  • zgc:153632
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits actin filament binding activity; protein-macromolecule adaptor activity; and signaling receptor binding activity. Involved in several processes, including animal organ development; epiboly; and pharyngeal system development. Predicted to localize to several cellular components, including lamellipodium; microvillus; and ruffle. Is expressed in several structures, including head; mesoderm; nervous system; neural crest; and neural plate. Orthologous to human FSCN1 (fascin actin-bundling protein 1).
Genome Resources
Note
None
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
20 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fscn1a Human Ortholog
No data available
Associated With fscn1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR022768 Fascin domain
Family IPR010431 Fascin
Family IPR024703 Fascin, metazoans
Family IPR030146 Fascin-1
Homologous_superfamily IPR008999 Actin-crosslinking
Domain Details Per Protein
Protein Length Actin-crosslinking Fascin Fascin-1 Fascin domain Fascin, metazoans
UniProtKB:Q08C47 491
UniProtKB:F1QET7 491
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-fscn1 monoclonal IgG Rabbit
  • IHC
Epitomics, Inc
3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations