Gene
ighv1-2
- ID
- ZDB-GENE-030924-2
- Name
- immunoglobulin heavy variable 1-2
- Symbol
- ighv1-2 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- null
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Zhang et al., 2016
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ighv1-2-201
(1)
|
Ensembl | 384 nt |
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-204F11 |
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| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | GenBank:AY646245 (1) | 650 nt | ||
| Genomic | GenBank:BX649502 | 247387 nt | ||
| Polypeptide | GenPept:AAU06706 (1) | 217 aa |
No data available
- Basheer, F., Bulleeraz, V., Ngo, V.Q.T., Liongue, C., Ward, A.C. (2022) In vivo impact of JAK3 A573V mutation revealed using zebrafish. Cellular and molecular life sciences : CMLS. 79:322
- Chi, Y., Huang, Z., Chen, Q., Xiong, X., Chen, K., Xu, J., Zhang, Y., Zhang, W. (2018) Loss of runx1 function results in B cell immunodeficiency but not T cell in adult zebrafish.. Open Biology. 8(7):
- Lobbardi, R., Pinder, J., Martinez-Pastor, B., Theodorou, M., Blackburn, J.S., Abraham, B.J., Namiki, Y., Mansour, M., Abdelfattah, N.S., Molodtsov, A., Alexe, G., Toiber, D., de Waard, M., Jain, E., Boukhali, M., Lion, M., Bhere, D., Shah, K., Gutierrez, A., Stegmaier, K., Silverman, L.B., Sadreyev, R.I., Asara, J.M., Oettinger, M.A., Haas, W., Look, A.T., Young, R.A., Mostoslavsky, R., Dellaire, G., Langenau, D.M. (2017) TOX regulates growth, DNA repair, and genomic instability in T-cell Acute Lymphoblastic Leukemia. Cancer discovery. 7(11):1336-1353
- Seelye, S.L., Chen, P.L., Deiss, T.C., Criscitiello, M.F. (2016) Genomic organization of the zebrafish (Danio rerio) T cell receptor alpha/delta locus and analysis of expressed products. Immunogenetics. 68(5):365-79
- Zhang, B., Shimada, Y., Hirota, T., Ariyoshi, M., Kuroyanagi, J., Nishimura, Y., Tanaka, T. (2016) Novel immunologic tolerance of human cancer cell xenotransplants in zebrafish. Translational research : the journal of laboratory and clinical medicine. 170:89-98.e3
- Seiler, C., Gebhart, N., Zhang, Y., Shinton, S.A., Li, Y.S., Ross, N.L., Liu, X., Li, Q., Bilbee, A.N., Varshney, G.K., LaFave, M.C., Burgess, S.M., Balciuniene, J., Balciunas, D., Hardy, R.R., Kappes, D.J., Wiest, D.L., Rhodes, J. (2015) Mutagenesis Screen Identifies agtpbp1 and eps15L1 as Essential for T lymphocyte Development in Zebrafish. PLoS One. 10:e0131908
- Hess, I., Iwanami, N., Schorpp, M., and Boehm, T. (2013) Zebrafish model for allogeneic hematopoietic cell transplantation not requiring preconditioning. Proceedings of the National Academy of Sciences of the United States of America. 110(11):4327-32
- Jiang, N., Weinstein, J.A., Penland, L., White, R.A., Fisher, D.S., and Quake, S.R. (2011) Determinism and stochasticity during maturation of the zebrafish antibody repertoire. Proceedings of the National Academy of Sciences of the United States of America. 108(13):5348-53
- Moss, L.D., Monette, M.M., Jaso-Friedmann, L., Leary, J.H. 3rd, Dougan, S.T., Krunkosky, T., and Evans, D.L. (2009) Identification of phagocytic cells, NK-like cytotoxic cell activity and the production of cellular exudates in the coelomic cavity of adult zebrafish. Developmental and comparative immunology. 33(10):1077-1087
- Weinstein, J.A., Jiang, N., White, R.A. 3rd, Fisher, D.S., and Quake, S.R. (2009) High-throughput sequencing of the zebrafish antibody repertoire. Science (New York, N.Y.). 324(5928):807-810
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