Gene
vax2
- ID
- ZDB-GENE-030904-8
- Name
- ventral anterior homeobox 2
- Symbol
- vax2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Exhibits sequence-specific DNA binding activity. Involved in camera-type eye morphogenesis; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and nervous system development. Predicted to localize to nucleus. Is expressed in diencephalon; forebrain neural rod; head; and immature eye. Orthologous to human VAX2 (ventral anterior homeobox 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 45 figures from 31 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | EMX/VAX/Noto Homeobox Transcription Factors | Helix-turn-helix motif | Homedomain-like superfamily | Homeobox, conserved site | Homeodomain |
|---|---|---|---|---|---|---|
|
UniProtKB:Q801E1
|
307 | |||||
|
UniProtKB:B3DIR5
|
307 |
Interactions and Pathways
No data available
Plasmids
No data available