Gene

vax2

ID
ZDB-GENE-030904-8
Name
ventral anterior homeobox 2
Symbol
vax2 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Enables sequence-specific DNA binding activity. Acts upstream of or within several processes, including camera-type eye morphogenesis; negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator; and regulation of retinal ganglion cell axon guidance. Predicted to be active in nucleus. Is expressed in diencephalon; forebrain neural rod; head; and immature eye. Orthologous to human VAX2 (ventral anterior homeobox 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
37 figures from 27 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vax2 Human Ortholog
No data available
Associated With vax2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR000047 Helix-turn-helix motif
Conserved_site IPR017970 Homeobox, conserved site
Domain IPR001356 Homeobox domain
Family IPR033021 Ventral anterior homeobox 2
Homologous_superfamily IPR009057 Homeobox-like domain superfamily
Domain Details Per Protein
Protein Length Helix-turn-helix motif Homeobox, conserved site Homeobox domain Homeobox-like domain superfamily Ventral anterior homeobox 2
UniProtKB:B3DIR5 307
UniProtKB:Q801E1 307
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations