ZFIN is now using GRCz12tu for Genomic Data
Gene

grk7b

ID
ZDB-GENE-030904-3
Name
G protein-coupled receptor kinase 7b
Symbol
grk7b Nomenclature History
Previous Names
  • gprk7
  • grk7-2 (1)
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Enables rhodopsin kinase activity. Predicted to be involved in regulation of signal transduction. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in brain and visual system. Orthologous to human GRK7 (G protein-coupled receptor kinase 7).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
9 figures from 8 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With grk7b Human Ortholog
No data available
Associated With grk7b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008271 Serine/threonine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Domain IPR000961 AGC-kinase, C-terminal
Domain IPR016137 RGS domain
Family IPR000239 GPCR kinase
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036305 RGS domain superfamily
Homologous_superfamily IPR044926 RGS, subdomain 2
Domain Details Per Protein
Protein Additional Resources Length AGC-kinase, C-terminal GPCR kinase Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily RGS domain RGS domain superfamily RGS, subdomain 2 Serine/threonine-protein kinase, active site
UniProtKB:Q49HM8 InterPro 548
UniProtKB:Q1XHL7 InterPro 548
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA grk7b-201 (1)
Ensembl
Ensembl 1,820 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab4-grk7 polyclonal Rabbit
  • IHC
  • WB
 2
Ab1-grk7b polyclonal Guinea pig
  • IHC
 1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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