Gene

prdx3

ID
ZDB-GENE-030826-18
Name
peroxiredoxin 3
Symbol
prdx3 Nomenclature History
Previous Names
  • cb718 (1)
  • wu:fk49e09
  • zgc:110282
  • zgc:112512
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Is predicted to enable thioredoxin peroxidase activity. Involved in cell redox homeostasis and cellular response to oxidative stress. Is expressed in several structures, including alar plate midbrain region; digestive system; eye; midbrain; and musculature system. Orthologous to human PRDX3 (peroxiredoxin 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With prdx3 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Corneal dystrophy, punctiform and polychromatic pre-Descemet 619871
Spinocerebellar ataxia, autosomal recessive 32 619862
Associated With prdx3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant
Domain IPR013766 Thioredoxin domain
Domain IPR019479 Peroxiredoxin, C-terminal
Homologous_superfamily IPR036249 Thioredoxin-like superfamily
Domain Details Per Protein
Protein Length Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant Peroxiredoxin, C-terminal Thioredoxin domain Thioredoxin-like superfamily
UniProtKB:A8E7G6 281
UniProtKB:Q568I5 250
UniProtKB:A8E7G7 240
UniProtKB:Q5BJB9 250
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations