Gene

xiap

ID
ZDB-GENE-030825-7
Name
X-linked inhibitor of apoptosis
Symbol
xiap Nomenclature History
Previous Names
  • XIAP (1)
  • birc4 (1)
  • fb73d01
  • wu:fb73d01 (1)
  • zgc:91873 (1)
Type
protein_coding_gene
Location
Chr: 14 Mapping Details/Browsers
Description
Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Predicted to be involved in several processes, including negative regulation of apoptotic process; positive regulation of canonical Wnt signaling pathway; and positive regulation of protein ubiquitination. Predicted to be active in cytoplasm; nucleus; and spindle microtubule. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to human XIAP (X-linked inhibitor of apoptosis).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With xiap Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
X-linked lymphoproliferative syndrome 2 Alliance Lymphoproliferative syndrome, X-linked, 2 300635
Associated With xiap Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001841 Zinc finger, RING-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Repeat IPR001370 BIR repeat
Domain Details Per Protein
Protein Length BIR repeat Zinc finger, RING/FYVE/PHD-type Zinc finger, RING-type
UniProtKB:A2RV08 405
UniProtKB:I6L9G1 322
UniProtKB:Q7SXU1 415
UniProtKB:Q8UWH2 405
UniProtKB:F1QMW2 405
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations