Gene

piwil1

ID
ZDB-GENE-030813-2
Name
piwi-like RNA-mediated gene silencing 1
Symbol
piwil1 Nomenclature History
Previous Names
  • ziwi (1)
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Enables piRNA binding activity. Involved in several processes, including gene silencing by RNA; germ cell development; and piRNA metabolic process. Located in P granule. Is expressed in several structures, including blastodisc; central nervous system; eye; reproductive system; and unfertilized egg. Orthologous to several human genes including PIWIL1 (piwi like RNA-mediated gene silencing 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
29 figures from 21 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Houwing et al., 2007
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With piwil1 Human Ortholog
No data available
Associated With piwil1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR003100 PAZ domain
Domain IPR003165 Piwi domain
Domain IPR031320 GAGE
Family IPR031326 Piwi-like protein 1
Homologous_superfamily IPR012337 Ribonuclease H-like superfamily
Homologous_superfamily IPR036085 PAZ domain superfamily
Homologous_superfamily IPR036397 Ribonuclease H superfamily
Domain Details Per Protein
Protein Length GAGE PAZ domain PAZ domain superfamily Piwi domain Piwi-like protein 1 Ribonuclease H-like superfamily Ribonuclease H superfamily
UniProtKB:A0A0J9YJF9 171
UniProtKB:A0A0R4IWH9 143
UniProtKB:Q8UVX0 858
UniProtKB:E9QHH1 230
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab2-piwil1 polyclonal Rabbit
1
AB4-piwil1 polyclonal Rabbit
  • WB
2
Ab1-piwil1 polyclonal Rabbit
  • IHC
  • WB
6
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations