Gene

tnr

ID

ZDB-GENE-030804-1

Name

tenascin R (restrictin, janusin)

Symbol

tnr Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 2 Mapping Details/Browsers

Description

Involved in axon guidance. Predicted to localize to collagen-containing extracellular matrix. Is expressed in brain; diencephalon; head; optic tectum; and retinal outer plexiform layer. Orthologous to human TNR (tenascin R).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Becker et al., 2003
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tnr Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Neurodevelopmental disorder, nonprogressive, with spasticity and transient opisthotonus	619653

Associated With tnr Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR020837	Fibrinogen, conserved site
Domain	IPR000742	EGF-like domain
Domain	IPR002181	Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
Domain	IPR003961	Fibronectin type III
Domain	IPR041161	Tenascin, EGF-like domain
Homologous_superfamily	IPR013783	Immunoglobulin-like fold
Homologous_superfamily	IPR014716	Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1
Homologous_superfamily	IPR036056	Fibrinogen-like, C-terminal
Homologous_superfamily	IPR036116	Fibronectin type III superfamily

Domain Details Per Protein

Protein	Length	EGF-like domain	Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain	Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1	Fibrinogen, conserved site	Fibrinogen-like, C-terminal	Fibronectin type III	Fibronectin type III superfamily	Immunoglobulin-like fold	Tenascin, EGF-like domain
UniProtKB:Q7T3T6 InterPro	1350
UniProtKB:A0A8M2BIJ4 InterPro	1261

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	tnr-201 (1) Ensembl	Havana	5056 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	tnr-202 (1) Ensembl	Havana	468 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-tnr		tnr			IHC WB		1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations