Gene
cxcl12b
- ID
- ZDB-GENE-030721-1
- Name
- chemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)
- Symbol
- cxcl12b Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Exhibits chemoattractant activity. Involved in several processes, including blood vessel morphogenesis; induction of positive chemotaxis; and nervous system development. Predicted to localize to extracellular region. Human ortholog(s) of this gene implicated in breast carcinoma; diabetic angiopathy; human immunodeficiency virus infectious disease; and type 1 diabetes mellitus. Is expressed in several structures, including cardiovascular system; central nervous system; endoderm; head; and mesoderm. Orthologous to human CXCL12 (C-X-C motif chemokine ligand 12).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 50 figures from 31 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- eu806 (14 images)
- eu815 (17 images)
Wild Type Expression Summary
- All Phenotype Data
- 14 figures from 9 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| {AIDS, resistance to} | 609423 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Chemokine beta/gamma/delta | Chemokine interleukin-8-like domain | Chemokine interleukin-8-like superfamily | CXC Chemokine domain |
|---|---|---|---|---|---|
|
UniProtKB:Q6V9B5
|
97 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cxcl12b-201
(1)
|
Ensembl | 2,844 nt |
Interactions and Pathways
No data available
Plasmids
No data available