ZFIN is now using GRCz12tu for Genomic Data
Gene
f9a
- ID
- ZDB-GENE-030714-2
- Name
- coagulation factor IXa
- Symbol
- f9a Nomenclature History
- Previous Names
-
- f9
- zgc:109775
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable serine-type endopeptidase activity. Predicted to be involved in blood coagulation and proteolysis. Predicted to act upstream of or within hemostasis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in blood plasma and liver. Used to study hemophilia B. Human ortholog(s) of this gene implicated in X-linked thrombophilia due to factor IX defect; X-linked warfarin sensitivity; and hemophilia B. Orthologous to human F9 (coagulation factor IX).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:109775 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Dhinoja et al., 2025
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| hemophilia B | Alliance | Hemophilia B | 306900 |
| X-linked thrombophilia due to factor IX defect | Alliance | Thrombophilia 8, X-linked, due to factor IX defect | 300807 |
| X-linked thrombophilia due to factor IX defect | Alliance | {Deep venous thrombosis, protection against} | 300807 |
| X-linked warfarin sensitivity | Alliance | {Warfarin sensitivity} | 301052 |
| Human Disease | Fish | Conditions | Citations |
|---|---|---|---|
| hemophilia B | f9azf4167/zf4167 | standard conditions | Dhinoja et al., 2025 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab-f9a | polyclonal | IgG | Rabbit |
|
Boster Biological
|
2 |
Plasmids
No data available
- Genome Browsers