ZFIN ID: ZDB-GENE-030710-1
Gene Name: reticulon 4a
Gene Symbol: rtn4a    Nomenclature History

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Previous Names: rtn4, Nogo-B (1), nogo (1), wu:fb17a02, wu:fb22f12, wu:fd61a07, zgc:92163

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Involved in several processes, including mesenchymal to epithelial transition; nervous system development; and sensory system development. Predicted to localize to endoplasmic reticulum; endoplasmic reticulum membrane; and integral component of membrane. Is expressed in several structures, including heart; liver; muscle; nervous system; and pectoral fin. Orthologous to human RTN4 (reticulon 4).
Genome Resources: Alliance (1),  Gene:447816 (1),  Ensembl(GRCz11):ENSDARG00000044601 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-rtn4a N/A 1
MO2-rtn4a N/A 1
MO3-rtn4a N/A 1
MO4-rtn4a N/A 1
MO5-rtn4a N/A 1
MO6-rtn4a N/A 1
MO7-rtn4a N/A 1
MO8-rtn4a N/A 1
MO9-rtn4a N/A 1
MO10-rtn4a N/A 1
MO11-rtn4a N/A 1
MO12-rtn4a N/A 1
MO13-rtn4a N/A 1
MO14-rtn4a N/A 1
MO15-rtn4a N/A 1
DISEASE ASSOCIATED WITH rtn4a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH rtn4a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process axonogenesis (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function protein binding (more)
GO Terms (all 17)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA rtn4a-201 (1)    Ensembl 2079
rtn4a-202 (1)    Ensembl 2138
rtn4a-203 (1)    Ensembl 1647
rtn4a-204 (1)    Ensembl 1887
ncRNA rtn4a-005 (1)    Ensembl 573
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-rtn4a polyclonal IgG Rabbit IHC, OTHR, WB 4
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM rtn4a
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
tg(actc1b:rtta,tetre:rtn4a,dsred,myl7:egfp) actc1bmyl7TETRE DsRedEGFPrtn4aRTTA Danio rerio 1 2
Tg(rtn4a-002:GFP) rtn4artn4a-204 GFP Danio rerio 1 2
Tg(rtn4a-003:GFP) rtn4artn4a-201 GFP Danio rerio 1 2
Tg(rtn4a-004:GFP) rtn4artn4a-203 GFP Danio rerio 1 2
MARKER RELATIONSHIPS
rtn4a Contained in: [BAC] DKEY-103K8 (1) (order this)
rtn4a Encodes: [EST] fb17a02, fb22f12, fd61a07
[cDNA] MGC:92163 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001079912 (1) 2145 nt
Genomic GenBank:BX324134 (1) 219514 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q4G5W2 (1) 322 aa
Sequence Information (all 48)
ORTHOLOGY for rtn4a ( Chr: 6 )
CITATIONS (36)