Gene

mgaa

ID
ZDB-GENE-030603-1
Name
MAX dimerization protein MGA a
Symbol
mgaa Nomenclature History
Previous Names
  • mga
  • im:7137698
  • sb:eu601
  • wu:fd99g02
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Contributes to transcription cis-regulatory region binding activity. Acts upstream of or within several processes, including SMAD protein signal transduction; determination of bilateral symmetry; and positive regulation of BMP signaling pathway. Part of SMAD protein complex. Is expressed in several structures, including gut; head; pectoral fin bud; and yolk syncytial layer. Orthologous to human MGA (MAX dimerization protein MGA).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mgaa Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Premature ovarian failure 26 621065
1 - 1 of 1
Associated With mgaa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018186 Transcription factor, T-box, conserved site
Domain IPR032060 MGA, conserved domain
Domain IPR046360 T-box transcription factor, DNA-binding domain
Family IPR001699 T-box transcription factor
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding domain superfamily
1 - 5 of 7 Show all
Domain Details Per Protein
Protein Additional Resources Length Helix-loop-helix DNA-binding domain superfamily MGA, conserved domain p53-like transcription factor, DNA-binding domain superfamily T-box superfamily T-box transcription factor T-box transcription factor, DNA-binding domain Transcription factor, T-box, conserved site
UniProtKB:A0A8M2B518 InterPro 2811
UniProtKB:D2JVK2 InterPro 2735
UniProtKB:A0A8M2B5I7 InterPro 2838
UniProtKB:F1R7N7 InterPro 2735
UniProtKB:A0A8M2B523 InterPro 2837
1 - 5 of 6 Show all
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mgaa-201 (1)
Ensembl
Ensembl 11,692 nt
ZFIN BLAST
mRNA mgaa-202 (1)
Ensembl
Ensembl 538 nt
ZFIN BLAST
mRNA mgaa-203 (1)
Ensembl
Ensembl 11,931 nt
ZFIN BLAST
mRNA mgaa-204 (1)
Ensembl
Ensembl 251 nt
ZFIN BLAST
mRNA mgaa-205 (1)
Ensembl
Ensembl 11,914 nt
ZFIN BLAST
1 - 5 of 7 Show all
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-mgaa
1
Ab1-mgaa
  • IHC
 1
Ab2-mgaa
  • IHC
 1
1 - 3 of 3
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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