Gene

mgaa

ID
ZDB-GENE-030603-1
Name
MAX dimerization protein MGA a
Symbol
mgaa Nomenclature History
Previous Names
  • mga
  • im:7137698
  • sb:eu601
  • wu:fd99g02
Type
protein_coding_gene
Location
Chr: 17 Mapping Details/Browsers
Description
Contributes to transcription regulatory region DNA binding activity. Involved in several processes, including animal organ development; determination of ventral identity; and positive regulation of BMP signaling pathway. Localizes to SMAD protein complex. Is expressed in several structures, including gut; head; pectoral fin bud; and yolk syncytial layer. Orthologous to human MGA (MAX dimerization protein MGA).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
11 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mgaa Human Ortholog
No data available
Associated With mgaa Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018186 Transcription factor, T-box, conserved site
Domain IPR032060 MGA, conserved domain
Domain IPR046360 T-box transcription factor, DNA-binding domain
Family IPR001699 T-box transcription factor
Homologous_superfamily IPR008967 p53-like transcription factor, DNA-binding domain superfamily
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Homologous_superfamily IPR036960 T-box superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily MGA, conserved domain p53-like transcription factor, DNA-binding domain superfamily T-box superfamily T-box transcription factor T-box transcription factor, DNA-binding domain Transcription factor, T-box, conserved site
UniProtKB:A0A8M2B518 2811
UniProtKB:D2JVK2 2735
UniProtKB:A0A8M2B5I7 2838
UniProtKB:F1R7N7 2735
UniProtKB:A0A8M2B523 2837
UniProtKB:A0A8M2B516 2837
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA mgaa-201 (1) Ensembl 11,692 nt
mRNA mgaa-202 (1) Ensembl 538 nt
mRNA mgaa-203 (1) Ensembl 11,931 nt
mRNA mgaa-204 (1) Ensembl 251 nt
mRNA mgaa-205 (1) Ensembl 11,914 nt
mRNA mgaa-206 (1) Ensembl 11,917 nt
mRNA mgaa-207 (1) Ensembl 12,001 nt
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-mgaa
1
Ab1-mgaa
  • IHC
1
Ab2-mgaa
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations