Gene

mgaa

ID

ZDB-GENE-030603-1

Name

MAX dimerization protein MGA a

Symbol

mgaa Nomenclature History

Previous Names

mga
im:7137698
sb:eu601
wu:fd99g02

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Description

Contributes to transcription regulatory region DNA binding activity. Involved in several processes, including animal organ development; determination of ventral identity; and positive regulation of BMP signaling pathway. Localizes to SMAD protein complex. Is expressed in several structures, including gut; head; pectoral fin bud; and yolk syncytial layer. Orthologous to human MGA (MAX dimerization protein MGA).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 5 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:7137698 (1 image)
eu601 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 11 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mgaa Human Ortholog

No data available

Associated With mgaa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR018186	Transcription factor, T-box, conserved site
Domain	IPR032060	MGA, conserved domain
Domain	IPR046360	T-box transcription factor, DNA-binding domain
Family	IPR001699	T-box transcription factor
Homologous_superfamily	IPR008967	p53-like transcription factor, DNA-binding domain superfamily
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily
Homologous_superfamily	IPR036960	T-box superfamily

Domain Details Per Protein

Protein	Length	Helix-loop-helix DNA-binding domain superfamily	MGA, conserved domain	p53-like transcription factor, DNA-binding domain superfamily	T-box superfamily	T-box transcription factor	T-box transcription factor, DNA-binding domain	Transcription factor, T-box, conserved site
UniProtKB:A0A8M2B518 InterPro	2811
UniProtKB:D2JVK2 InterPro	2735
UniProtKB:A0A8M2B5I7 InterPro	2838
UniProtKB:F1R7N7 InterPro	2735
UniProtKB:A0A8M2B523 InterPro	2837
UniProtKB:A0A8M2B516 InterPro	2837

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mgaa-202 (1) Ensembl	Havana	538 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	mgaa-203 (1) Ensembl	Havana	11931 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	mgaa-204 (1) Ensembl	Havana	251 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

Name	Antigen Genes	Assay	Citations
Ab3-mgaa	mgaa		1
Ab1-mgaa	mgaa	IHC	1
Ab2-mgaa	mgaa	IHC	1

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations