ZFIN ID: ZDB-GENE-030520-1
Gene Name: troponin T2c, cardiac
Gene Symbol: tnnt2c    Nomenclature History

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Previous Names: tnnt1, cb328 (1), sb:cb328, zgc:86847

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Involved in sarcomere organization. Predicted to localize to troponin complex. Is expressed in mesoderm; musculature system; somite; and trunk mesenchyme. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Orthologous to human TNNT2 (troponin T2, cardiac type).
Genome Resources: Alliance (1),  Gene:353248 (1),  Ensembl(GRCz11):ENSDARG00000032242 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa224 Point Mutation Unknown Premature Stop ENU
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-tnnt2c N/A 1
DISEASE ASSOCIATED WITH tnnt2c HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH tnnt2c VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process sarcomere organization (more)
Cellular Component troponin complex (more)
Molecular Function CONTRIBUTES_TO   calcium-dependent ATPase activity (more)
GO Terms (all 11)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA tnnt2c-201 (1)    Ensembl 1909
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM tnnt2c No data available
MARKER RELATIONSHIPS
tnnt2c Contained in: [BAC] DKEY-222F8 (1) (order this)
tnnt2c Encodes: [EST] cb328 (1) (order this), cegs953 (1) (order this), eu913 (1)
[cDNA] MGC:86847 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_181499 (1) 1917 nt
Genomic GenBank:BX005210 (1) 207949 nt Blast at MegaBLAST
Polypeptide UniProtKB:Q8AVB1 (1) 290 aa
Sequence Information (all 16)
ORTHOLOGY for tnnt2c ( Chr: 4 )
CITATIONS (32)