Gene
tnnt2c
- ID
- ZDB-GENE-030520-1
- Name
- troponin T2c, cardiac
- Symbol
- tnnt2c Nomenclature History
- Previous Names
-
- tnnt1
- cb328 (1)
- sb:cb328
- zgc:86847
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to contribute to calcium-dependent ATPase activity and tropomyosin binding activity. Involved in sarcomere organization. Predicted to localize to troponin complex. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple). Is expressed in mesoderm; musculature system; somite; and trunk mesenchyme. Orthologous to human TNNT2 (troponin T2, cardiac type).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 26 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb328 (10 images)
- eu913 (12 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Ferrante et al., 2011
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Troponin | Troponin domain superfamily | Troponin T |
|---|---|---|---|---|
|
UniProtKB:Q8AVB1
|
290 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
tnnt2c-201
(1)
|
Ensembl | 1,909 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Comparative Orthology
- Alliance
- Gene Tree
- Ensembl
- Note
- Hsiao, et al. 2003 (ZDB-PUB-030516-1) reported orthology to human TNNT1 and mouse Tnnt1 based on amino acid similarity. Subsequent analysis suggests tnnt1 (ZDB-GENE-080723-27) is the zebrafish ortholog based on amino acid similarity and conserved location.