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Gene

srpra

ID
ZDB-GENE-030219-11
Name
SRP receptor subunit alpha
Symbol
srpra Nomenclature History
Previous Names
  • srpr
  • id:ibd1064
  • wu:fd12f02
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Predicted to enable GTPase activity and signal recognition particle binding activity. Predicted to be involved in protein targeting to ER. Predicted to act upstream of or within SRP-dependent cotranslational protein targeting to membrane. Predicted to be part of signal recognition particle receptor complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in brain. Orthologous to human SRPRA (SRP receptor subunit alpha).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Kudoh et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With srpra Human Ortholog
No data available
Associated With srpra Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain
Domain IPR003593 AAA+ ATPase domain
Domain IPR007222 Signal recognition particle receptor, alpha subunit, N-terminal
Domain IPR013822 Signal recognition particle SRP54, helical bundle
Homologous_superfamily IPR011012 Longin-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036225 SRP/SRP receptor, N-terminal
Homologous_superfamily IPR042101 Signal recognition particle SRP54, N-terminal domain superfamily
Domain Details Per Protein
Protein Length AAA+ ATPase domain Longin-like domain superfamily P-loop containing nucleoside triphosphate hydrolase Signal recognition particle receptor, alpha subunit, N-terminal Signal recognition particle SRP54, helical bundle Signal recognition particle SRP54, N-terminal domain superfamily Signal recognition particle, SRP54 subunit, GTPase domain SRP/SRP receptor, N-terminal
UniProtKB:E7EZW6 650
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations