Gene
srpra
- ID
- ZDB-GENE-030219-11
- Name
- SRP receptor subunit alpha
- Symbol
- srpra Nomenclature History
- Previous Names
-
- srpr
- id:ibd1064
- wu:fd12f02
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have GTPase activity and signal recognition particle binding activity. Predicted to be involved in protein targeting to ER. Predicted to localize to endoplasmic reticulum membrane. Is expressed in brain. Orthologous to human SRPRA (SRP receptor subunit alpha).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Kudoh et al., 2001
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Linder et al., 2022
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000897 | Signal recognition particle, SRP54 subunit, GTPase domain |
| Domain | IPR003593 | AAA+ ATPase domain |
| Domain | IPR007222 | Signal recognition particle receptor, alpha subunit, N-terminal |
| Domain | IPR013822 | Signal recognition particle SRP54, helical bundle |
| Homologous_superfamily | IPR011012 | Longin-like domain superfamily |
| Homologous_superfamily | IPR027417 | P-loop containing nucleoside triphosphate hydrolase |
| Homologous_superfamily | IPR036225 | SRP/SRP receptor, N-terminal |
| Homologous_superfamily | IPR042101 | Signal recognition particle SRP54, N-terminal domain superfamily |
Domain Details Per Protein
| Protein | Length | AAA+ ATPase domain | Longin-like domain superfamily | P-loop containing nucleoside triphosphate hydrolase | Signal recognition particle receptor, alpha subunit, N-terminal | Signal recognition particle SRP54, helical bundle | Signal recognition particle SRP54, N-terminal domain superfamily | Signal recognition particle, SRP54 subunit, GTPase domain | SRP/SRP receptor, N-terminal |
|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:E7EZW6
|
650 |
Interactions and Pathways
No data available
Plasmids
No data available