Gene

fgb

ID
ZDB-GENE-030131-9261
Name
fibrinogen beta chain
Symbol
fgb Nomenclature History
Previous Names
  • wu:fa55c11
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to contribute to signaling receptor binding activity. Involved in blood coagulation, fibrin clot formation. Predicted to localize to collagen-containing extracellular matrix and extracellular space. Is expressed in liver and yolk syncytial layer. Human ortholog(s) of this gene implicated in cardiovascular system disease (multiple); congenital afibrinogenemia; and end stage renal disease. Orthologous to human FGB (fibrinogen beta chain).
Genome Resources
Note
None
Expression
All Expression Data
12 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fgb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital afibrinogenemia Alliance Afibrinogenemia, congenital 202400
congenital afibrinogenemia Alliance Hypofibrinogenemia, congenital 202400
Dysfibrinogenemia, congenital 616004
Associated With fgb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
Domain IPR012290 Fibrinogen, alpha/beta/gamma chain, coiled coil domain
Family IPR037580 Fibrinogen beta chain
Homologous_superfamily IPR036056 Fibrinogen-like, C-terminal
Domain Details Per Protein
Protein Length Fibrinogen, alpha/beta/gamma chain, coiled coil domain Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain Fibrinogen beta chain Fibrinogen-like, C-terminal
UniProtKB:Q6NYE1 485
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations