ZFIN ID: ZDB-GENE-030131-9122
Gene Name: SMG7 nonsense mediated mRNA decay factor
Gene Symbol: smg7    Nomenclature History

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Previous Names: fa99h10, wu:fa99h10 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have telomerase RNA binding activity and telomeric DNA binding activity. Involved in chordate embryonic development. Predicted to localize to cytoplasm and telomerase holoenzyme complex. Orthologous to human SMG7 (SMG7 nonsense mediated mRNA decay factor).
Genome Resources: Alliance (1),  Gene:565575 (1),  Ensembl(GRCz11):ENSDARG00000060767 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu2439]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa853 Point Mutation Unknown Premature Stop ENU
sa18100 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19816 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32963 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-smg7 N/A 1
    DISEASE ASSOCIATED WITH smg7 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH smg7 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process chordate embryonic development (more)
    Cellular Component telomerase holoenzyme complex (more)
    Molecular Function transferase activity (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA smg7-202 (1)    Ensembl 4088
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM smg7 No data available
    MARKER RELATIONSHIPS
    smg7 Contained in: [BAC] DKEY-161L11 (order this)
    smg7 Encodes: [EST] eu2439 (1), fa99h10
    [cDNA] MGC:194406 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001045083 (1) 3729 nt
    Genomic GenBank:BX681417 (1) 233760 nt Blast at MegaBLAST
    Polypeptide UniProtKB:Q1LVF3 (1) 1180 aa
    Sequence Information (all 20)
    ORTHOLOGY for smg7 ( Chr: 2 )
    CITATIONS (25)