sod3b

ID

ZDB-GENE-030131-8743

Name

superoxide dismutase 3, extracellular b

Symbol

sod3b Nomenclature History

Previous Names

sod3
fb05f10
si:dkey-117m1.6
wu:fb05f10 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Enables heparin binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Predicted to act upstream of or within superoxide metabolic process. Is expressed in several structures, including eye; head mesenchyme; hyaloid vessel; male organism; and skeletal system. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

11 figures from 9 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With sod3b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Superoxide dismutase, elevated extracellular]

Associated With sod3b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018152	Superoxide dismutase, copper/zinc, binding site
Domain	IPR001424	Superoxide dismutase, copper/zinc binding domain
Family	IPR024134	Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone
Homologous_superfamily	IPR036423	Superoxide dismutase-like, copper/zinc binding domain superfamily