Gene
sod3b
- ID
- ZDB-GENE-030131-8743
- Name
- superoxide dismutase 3, extracellular b
- Symbol
- sod3b Nomenclature History
- Previous Names
-
- sod3
- fb05f10
- si:dkey-117m1.6
- wu:fb05f10 (1)
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Description
- Enables heparin binding activity and superoxide dismutase activity. Acts upstream of or within removal of superoxide radicals. Is expressed in several structures, including eye; head mesenchyme; hyaloid vessel; male organism; and skeletal system. Human ortholog(s) of this gene implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Orthologous to human SOD3 (superoxide dismutase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 11 figures from 9 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| [Superoxide dismutase, elevated extracellular] |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR018152 | Superoxide dismutase, copper/zinc, binding site |
| Domain | IPR001424 | Superoxide dismutase, copper/zinc binding domain |
| Family | IPR024134 | Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone |
| Homologous_superfamily | IPR036423 | Superoxide dismutase-like, copper/zinc binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Superoxide dismutase, copper/zinc binding domain | Superoxide dismutase, copper/zinc, binding site | Superoxide dismutase (Cu/Zn) / superoxide dismutase copper chaperone | Superoxide dismutase-like, copper/zinc binding domain superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:E9QIM2 | InterPro | 192 |
Interactions and Pathways
No data available
Plasmids
No data available