Gene
lrp11
- ID
- ZDB-GENE-030131-7847
- Name
- low density lipoprotein receptor-related protein 11
- Symbol
- lrp11 Nomenclature History
- Previous Names
-
- si:dkey-181i3.7
- wu:fj36e03
- Type
- protein_coding_gene
- Location
- Chr: 20 Mapping Details/Browsers
- Description
- Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be located in membrane. Orthologous to human LRP11 (LDL receptor related protein 11).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
No data available
No data available
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR020901 | Proteinase inhibitor I2, Kunitz, conserved site |
| Conserved_site | IPR023415 | Low-density lipoprotein (LDL) receptor class A, conserved site |
| Domain | IPR002223 | Pancreatic trypsin inhibitor Kunitz domain |
| Domain | IPR011106 | Seven cysteines, N-terminal |
| Domain | IPR013980 | MANSC domain |
1 - 5 of 10 Show all
Domain Details Per Protein
| Protein | Additional Resources | Length | Immunoglobulin-like fold | LDL receptor-like superfamily | Low-density lipoprotein (LDL) receptor class A, conserved site | Low-density lipoprotein (LDL) receptor class A repeat | MANSC domain | Pancreatic trypsin inhibitor Kunitz domain | Pancreatic trypsin inhibitor Kunitz domain superfamily | PKD domain superfamily | Proteinase inhibitor I2, Kunitz, conserved site | Seven cysteines, N-terminal |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:F1QHM0 | InterPro | 429 | ||||||||||
| UniProtKB:A0A8M2B7G6 | InterPro | 544 |
1 - 2 of 2
Interactions and Pathways
No data available
Plasmids
No data available
No data available
| Relationship | Marker Type | Marker | Accession Numbers | Citations |
|---|---|---|---|---|
| Contained in | BAC | DKEY-181I3 | ZFIN Curated Data | |
| Encodes | EST | fj36e03 |
1 - 2 of 2
Show
| Type | Accession # | Sequence | Length (nt/aa) | Analysis |
|---|---|---|---|---|
| RNA | RefSeq:NM_001122874 (1) | 1837 nt | ||
| Genomic | GenBank:BX248418 (1) | 152757 nt | ||
| Polypeptide | UniProtKB:A0A8M2B7G6 (1) | 544 aa |
- Liu, Z., Zhang, N., Wang, C., Shi, L., Hu, Y., Wang, Y., Li, J. (2024) Lrp13a and Lrp13b serve as vitellogenin receptors in the ovary of zebrafish†. Biology of reproduction. 111(1):123-134
- Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549
- Reading, B.J., Hiramatsu, N., Schilling, J., Molloy, K.T., Glassbrook, N., Mizuta, H., Luo, W., Baltzegar, D.A., Williams, V.N., Todo, T., Hara, A., Sullivan, C.V. (2014) Lrp13 is a novel vertebrate lipoprotein receptor that binds vitellogenins in teleost fishes. Journal of Lipid Research. 55(11):2287-95
1 - 3 of 3
Show